Antibodies that detect Dynactin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Dynactin 1 in Human, Mouse, Rat, Canine and Non-human primate samples. Our...Antibodies that detect Dynactin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Dynactin 1 in Human, Mouse, Rat, Canine and Non-human primate samples. Our Dynactin 1 polyclonal and monoclonal...Antibodies that detect Dynactin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Dynactin 1 in Human, Mouse, Rat, Canine and Non-human primate samples. Our Dynactin 1 polyclonal and monoclonal antibodies are developed in Rabbit, Sheep, Mouse and Goat. These antibodies have been verified by Knockdown to confirm specificity to Dynactin 1. Find the Dynactin 1 antibody that fits your needs. Choose from 1 of 19 Dynactin 1 antibodies, which have been validated in experiments with 16 publications and 60 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect Dynactin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Dynactin 1 in Human, Mouse, Rat, Canine and Non-human primate samples. Our Dynactin 1 polyclonal and monoclonal antibodies are developed in Rabbit, Sheep, Mouse and Goat. These antibodies have been verified by Knockdown to confirm specificity to Dynactin 1. Find the Dynactin 1 antibody that fits your needs. Choose from 1 of 19 Dynactin 1 antibodies, which have been validated in experiments with 16 publications and 60 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).
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